Identifying drug combinations for the treatment of muscular dystrophy (U.S.) The general goal of this project was to perform high-throughput screening of already existing and FDA-approved drugs, which in combination may lead to modifications of various targets, which have been shown to be promising in the treatment of muscular dystrophy. Specifically, this project was analysing [...]
Past Projects
Upregulate Utrophin
Identifying a small molecule to upregulate utrophin expression in skeletal muscle (UK) Previous evidence suggest that upregulation of utrophin can compensate for the loss of dystrophin, which makes this protein an excellent candidate for therapy. This project initiated by Summit Plc and now Biomarin (US) revealed two promising candidates, which have been tested in animal [...]